The global liver cirrhosis market size is projected to be worth USD 1.49 billion in 2025. It can scale to a valuation of USD 2.15 billion by 2032. The market is anticipated to exhibit a CAGR of 5.4% during the forecast period (2025-2032).
The surge in cases of liver disorders and advances in liver transplants are primary drivers of the market. Improvements in healthcare infrastructure and approvals for new drugs for the treatment of liver diseases can bolster the market growth over the forecast period.
However, the high treatment costs can act as a deterrent for the market.
Key Market Insights
The liver cirrhosis market growth is driven by AI-fueled diagnostic workflows, approval of novel drugs, and focus on metabolic cirrhosis.
- By etiology, the nonalcoholic fatty liver disease (NAFLD) segment is expected to capture a 35.0% share of the market in 2025. Rising cases of obesity and NAFLD being a primary cause of liver disease are factors driving the segment growth.
- By treatment, the liver transplantation segment is anticipated to attain a 38.0% market share in 2025. This can be attributed to the rise in organ donatio It is illustrated in the report by the Organ Procurement and Transplantation Network (OPTN), with liver transplantation operations exceeding 48,000 in 2024. Improvements in transplantation surgeries are also expected to drive the segment till 2032.
- By disease stage, the decompensated cirrhosis segment is anticipated to attain 38.0% market share in 2025. The prevalence of cases of metabolic liver disease and liver cirrhosis can drive the segment growth over the forecast period.
- By end user, the hospitals & clinics segment is anticipated to lead with a 45% market share in 2025. This can be attributed to hospitals and clinics containing advanced diagnostic centers and specialized pharmacies. The large number of liver transplantation procedures being conducted in hospitals is another major driver of the segment.
- By geography, Asia Pacific is expected to capture 37% market share in 2025 owing to a large portion of Hepatitis B cases and a large chunk of healthcare expenditure dedicated to liver cirrhosis. Rise in medical tourism focusing on liver care can contribute to the regional liver cirrhosis market growth.
The full report is now available for purchase:
https://www.coherentmi.com/industry-reports/liver-cirrhosis-marketLiver Cirrhosis Market Report Coverage
Report Coverage
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Details
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Market Revenue in 2025
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USD 1.49 billion
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Estimated Value by 2032
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USD 2.15 billion
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Growth Rate
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5.4%
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Historical Data
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2020–2024
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Forecast Period
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2025–2032
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Forecast Units
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Value (USD billion)
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Report Coverage
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Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
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Segments Covered
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By Etiology, Treatment, Disease Stage, and End User
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Geographies Covered
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North America (U.S. and Canada), Latin America (Brazil, Argentina, Mexico, and Rest of Latin America), Europe (Italy, Spain, U.K., Germany, France, Russia, and Rest of Europe), Asia Pacific (China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific), Middle East (GCC Countries, Israel, and Rest of Middle East), and Africa (South Africa, North Africa, and Central Africa)
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Growth Drivers
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Opportunities
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Trends
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Restraints & Challenges
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Market Dynamics
The rising prevalence of fatty liver diseases like metabolic dysfunction-associated steatohepatitis (MASH) is anticipated to drive the market growth. Investment in clinical trials for the approval of novel drugs such as semaglutide and pemvidutide by prominent pharmaceutical manufacturers can drive the liver cirrhosis market growth. The acceptance of these drugs by health regulatory authorities can be the first step in achieving treatment for patients with MASH.
Development of novel regenerative treatments for the treatment of late-stage chronic liver diseases can boost the market growth. Ochre Bio and Boehringer Ingelheim decided to collaborate on April 22, 2024, for the discovery and development of new treatments for liver diseases. It will leverage human data and disease models to expedite the development of new drugs.
Market Opportunity:
Use of AI for Faster Detection of Liver Diseases
The use of artificial intelligence (AI) screening tools for faster detection of liver diseases is expected to be a prime opportunity for the liver cirrhosis market. Rising cases of NAFLD is predicted to drive the demand for AI in diagnostic labs. The prevalence of obesity and diabetes is driving the development of NAFLD among patients.
On June 20, 2025, a study by a research group at Osaka Metropolitan University's Graduate School of Medicine developed an AI model for the detection of fatty liver disease using chest X-rays. The model was successful after the study of 6,599 radiographs from 4,414 patients.
Market Challenge: High Treatment Costs to Affect Market Growth
The high financial burden for the treatment of liver cirrhosis can present a significant challenge to the market growth. This includes hospitalization expenses, doctor fees, medications, and post-operative care. The financial burden on economically weak nations with limited access to good surgeons and transplantation options can also limit the market growth. However, a higher insurance coverage for liver diseases and financial stimulus packages by governments for patients with liver cirrhosis can bode favorably for the market.
Analyst’s View
- The rising cases of diabetes and obesity can drive the liver cirrhosis market growth.
- The use of AI workflows for faster detection of liver disease in the prevention stage can drive overall demand for liver cirrhosis treatments.
- Key players in the market are resorting to partnerships or investments in clinical trials to expedite drug development for the treatment of liver cirrhosis.
Recent Developments
Novo Nordisk’s weight loss drug, Wegovy, can be considered for approval for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) by the U.S. FDA by the end of 2025.
Competitor Insights
- Madrigal Pharmaceuticals, Inc.
- Galectin Therapeutics Inc.
- Grifols Therapeutics LLC
- CymaBay Therapeutics
- Akero Therapeutics, Inc.
- NGM Biopharmaceuticals, Inc.
- Gilead Sciences
- Novo Nordisk A/S
- Cellaion
- Promethera Therapeutics
Market Segmentation
- By Etiology
- Alcoholic Liver Cirrhosis
- Nonalcoholic Fatty Liver Disease (NAFLD)
- Viral Hepatitis
- Other Causes
- By Treatment
- Ursodeoxycholic Acid (UDCA)
- Corticosteroids
- Antiviral Drugs
- Medication
- Liver Transplantation
- Supportive Care
- By Disease Stage
- Compensated Cirrhosis
- Decompensated Cirrhosis
- By End User
- Hospitals
- Specialty Clinics
- Ambulatory Surgical Centers
- Academic & Research Institutes
- Others
Regional Insights
- North America
- U.S.
- Canada
- Latin America
- Brazil
- Argentina
- Mexico
- Rest of Latin America
- Europe
- Germany
- U.K.
- Spain
- France
- Italy
- Russia
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- GCC Countries
- Israel
- Rest of Middle East
- Africa
- South Africa
- North Africa
- Central Africa